Oncology drug development company Celsion recently spoke about its recent development in the way of helping those with brain cancer. Specifically, the company would focus on glioblastoma, which is commonly regarded in this field of research. It's not hard to see why, as this particular tumor has been considered the most serious and aggressive form of tumor in the brain. Can a new approach by this company, though, prove to be helpful for not only patients who are afflicted but the entire scope of research seen here?
Pharmaceutical Business Review posted an article on the matter and it seems as though the potential is clear. There is an approach to be had, which can possibly become able to treat tumors in the brain, glioblastoma being the main focus of this approach. It is one that has been given the focus of various organizations - Voices against Brain Cancer as just one example - so what exactly does this approach by Celsion entail? There are a couple of details that, in my opinion, deserve to be gone over.
The company will put forth experiments that will determine the effectiveness of ThermoDox in conjunction with MR guided high intensity focused ultrasound. The focus will be placed on animal models first before, if successful, being parlayed into human use. According to Dr. Nicholas Borys, ThermoDox is a "heat-activated liposomal encapsulation of doxorubicin," which would be able to provide clinical benefit. It has also been utilized for the sake of treating other types of cancer, which lends credence to the idea that it could come into play in this field as well.
The report also detailed a phase III HEAT study that could, in theory, prove the effectiveness of ThermoDox along with RFA. Would patients be able to react positively to this combination, one would have to wonder? After the results were found, it was determined that ThermoDox could prove to be useful for the sake of improving PFS degrees. Seeing as how survival rates could be made greater for patients stricken with cancer, to say that results can stand to be great would be an understatement.
I have to believe that greater results can come to the surface in due time. In my mind, the ThermoDox approach holds tremendous potential, especially when given how the approach has been utilized in the past. Liver cancer, for example, has been focused on and the same could be said about other forms of this condition as well. By this information, it appears as though there are results to be had when it comes to helping patients that have been stricken with brain cancer as well.
Pharmaceutical Business Review posted an article on the matter and it seems as though the potential is clear. There is an approach to be had, which can possibly become able to treat tumors in the brain, glioblastoma being the main focus of this approach. It is one that has been given the focus of various organizations - Voices against Brain Cancer as just one example - so what exactly does this approach by Celsion entail? There are a couple of details that, in my opinion, deserve to be gone over.
The company will put forth experiments that will determine the effectiveness of ThermoDox in conjunction with MR guided high intensity focused ultrasound. The focus will be placed on animal models first before, if successful, being parlayed into human use. According to Dr. Nicholas Borys, ThermoDox is a "heat-activated liposomal encapsulation of doxorubicin," which would be able to provide clinical benefit. It has also been utilized for the sake of treating other types of cancer, which lends credence to the idea that it could come into play in this field as well.
The report also detailed a phase III HEAT study that could, in theory, prove the effectiveness of ThermoDox along with RFA. Would patients be able to react positively to this combination, one would have to wonder? After the results were found, it was determined that ThermoDox could prove to be useful for the sake of improving PFS degrees. Seeing as how survival rates could be made greater for patients stricken with cancer, to say that results can stand to be great would be an understatement.
I have to believe that greater results can come to the surface in due time. In my mind, the ThermoDox approach holds tremendous potential, especially when given how the approach has been utilized in the past. Liver cancer, for example, has been focused on and the same could be said about other forms of this condition as well. By this information, it appears as though there are results to be had when it comes to helping patients that have been stricken with brain cancer as well.
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If you'd care for more information about glioblastoma, please consult Voices against Brain Cancer.
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